Level C. What happens if you have a neonate? Neonates are mostly water (much more so than adults) and often don’t have normal drug elimination due to immature kidneys.
These videos help explain why neonates need different dosing protocols. The powerpoints referred to are in the regulatory section but I think you can follow these without viewing those first.
Neonatal Adjustments. November 2003, Veterinary Clinics of North America Food Animal Practice 19(3):551-6, v
Note: the same principles apply for liver dysfunction and in neonates of other species: