Equine tendons and ligaments

Tendon and ligament structure and function

Structure

Tendons must have high tensile strength and elasticity and be able to glide across other tissues. Tendons are connected to muscle on one end and to bone on the other end. Fibrocatilage regions create zones of increasing stiffness at the tendon-bone junction. Tendons are comprised of an extracellular matrix of collagen, proteoglycans, glycosaminoglycans, and a few tenocytes. To create the high tensile strength, tendons are composed of type I collagen arranged in triple helix (tropocollagen) fibrils oriented parallel to the long axis of the tendon with a large amount of cross-linking. The cross-linking is possible due to the precise arrangement in healthy tendons. The tendons are arranged in bundles with an undulating pattern called crimp. This crimp structure permits stretching without tearing (elasticity).

In areas where the tendon has to make a course change (eg over the fetlock joint) , the tendon is usually surrounded by a tendon sheath. The tendon sheath is lined by synovium and forms a fluid filled cavity for the tendon.  A bursa is similar to a tendon sheath except it only covers part of the tendon surface. Bursae are found between tendons and bony prominences (eg bicipital bursa). In other areas, the tendon is surrounded the paratenon, an elastic connective tissue sheath with an excellent vascular supply.

Tendons are relatively acellular. Tenocytes obtain nutrition from penetrating vessels (from tendon sheaths, paratenon, bony attachment) and the synovial fluid if within a tendon sheath.

Compared to tendons, ligaments stretch less and fibers are arranged in less of a parallel fashion and are not crimped.  Ligaments may also contain skeletal muscle fibers. Ligaments are attached to bone on both ends or connect bone and tendons (so less stretch overall). Ligaments often function to bind bones together.

Pathology -Tendonitis/Desmitis

Tendons and ligaments respond to injury in the typical fashion with four overlapping phases of injury, inflammation, repair and remodeling. The final result is connective tissue scar.

Inflammation includes heat, pain, swelling and loss of use. Over the first 8 weeks, the tissue is a fibrovascular mass of immature collagen fibers with little strength. During remodeling, these fibers are replaced with type I collagen bundles oriented along the lines of tension. Strength improves 3 fold between weeks 8 and 12. By 24 weeks, the tendon scar is mature with longitudinally oriented fiber bundles. These bundles still contain some immature collagenous tissue; remodeling continues for many more months.

Hint : the number of letters = months of healing. Bone heals in ~ 4 months, tendons in ~ 6 months and ligaments in ~ 8-9 months.

Pathology – Suspensory ligament degeneration

Degenerative suspensory ligament disease seems to be the result of excessive accumulation of proteoglycans that weaken the ligament. The disease is considered heritable and there is no known cure. The proteoglycan accumulation can affect tendons and other connective tissue structures, as well. As the ligament loses strength, the fetlock drops. Horses are typically very lame with abnormal hindlimb conformation (dropped fetlocks).

Key Takeaways

Tendons connect muscle to bone. Ligaments do not connect to muscle and tend to be involved with limiting rather than permitting stretch.

Both tendons and ligaments contain large amounts of type I collagen.

Tendon fibers are crosslinked and aligned with weight bearing; when tendons are injured, they need weight bearing to know how to align.

Tendons are often associated with a tendon sheath or bursa when crossing bendable bits.

Tendons require about 6 months to heal (under good conditions), while ligaments require 8-9 months.

Suspensory ligaments can also degenerate and weaken. The condition is considered heritable.

 

License

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Large Animal Surgery - Supplemental Notes by Erin Malone, DVM, PhD; Elaine Norton, DVM PhD; Erica Dobbs, DVM; and Ashley Ezzo, DVM is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, except where otherwise noted.