51 The microbiome – Instructor Guide
Title
Why DO pandas eat bamboo?
Instructional guide
Pandas are obligate herbivores, eating only bamboo. Most herbivores use microbes to digest the grasses and hays; they do not produce the cellulase-type enzymes themselves. These animals have “fermentation vats” that house the microbes in the appropriate environment. Pandas do not have this and are trying to be herbivores without the appropriate microbes. This unit is designed to help students develop a working knowledge of animal GI tracts and to also develop a scientific approach to questions.
Student learning objectives
- Define “gut microbiome”
- Explain foregut and hindgut fermentation and how this would help pandas
- Uses horses, rabbits and cattle as examples
- Discuss how evolutionary forces might lead to a mismatch in diet and microbiome
- Practice identifying what background information is needed
- Research attempts to alter gut microbiome in other species
- Practice developing scientific proposals
Intended grade level
- This is designed for high school students wanting to pursue extra challenges
Format
- Research project
Space needed
- No specific needs
Estimated duration
- Students will need 2-3 hours to explore the problem and another 2-3 hours to develop and polish a plan
Materials needed
- White boards and post it notes could be very useful
Outline
- Student should work in small groups to
- identify learning needs (what do they need to know to tackle this problem)
- do research to answer their learning needs
- develop theories on evolutionary forces
- do more research to develop possible solutions
- design a research plan to “fix” the panda
Learning resources
- Students need access to resources, search engines and journal articles in the medical field
- Link to the student lesson page
Common misconceptions and challenge points
- It is hard to identify what you do and don’t know and how to start
Potential research avenues if students need direction:
- While cattle are ruminants, calves are not. They have to develop their rumen and its related microbiome.
- Horses can digest grasses but do not have a dedicated structure like a rumen. Instead, they have modified their colon to allow microbial fermentation. We can surgically remove most of the colon and they can adapt
- Rabbits eat their “night feces” to re-ingest the microbial products that would otherwise be lost
- Antibiotics can destroy any animals microbiome and it can be replaced at least partially using probiotics and fecal transplants
- Plants can be genetically modified
Other notes
- No one currently knows the answer
Knowledge check
- We suggest having the students present their theories to other students. If more than one group is working on this problem, groups could also compare their theories and vote on the one they would fund.
Feedback/Errata